Infection in both lungs may be caused by inflammation of the lungs due to bacterial, viral, fungal and other infections. If the anti-infection treatment is ineffective it may be caused by tuberculosis or tumor and other diseases, which can be treated by anti-tuberculosis treatment, radiotherapy, surgery and so on. 1. Ineffective treatment of infection in both lungs may be caused by tuberculosis, which is a chronic infectious disease caused by Mycobacterium tuberculosis infection. Symptoms such as prolonged low-grade fever, night sweats, cough, sputum, hemoptysis, etc. can be relieved by anti-tuberculosis drugs such as isoniazid, rifampicin and pyrazinamide. 2. Ineffective treatment of double-lung infection may be caused by tumor, which causes obstructive pneumonia, and there may be cough, blood in sputum, hemoptysis, low-grade fever, chest tightness, chest pain and dyspnea, etc. According to the pathology and staging of the tumor, radiotherapy, surgery and other treatments can be chosen to reduce tumor load, metastasis and recurrence. When the treatment of double lung infection is ineffective, the cause of the disease should be identified in time in the hospital, and cause-specific and symptomatic treatment should be carried out under the guidance of doctors.