Cranial repair surgery has been developed for thousands of years in the history of medicine, and the surgical technique has become more mature. Cranial bone repair materials have also undergone many improvements and innovations, and are becoming more and more advanced. At present, the more commonly used cranial bone repair material is titanium mesh, this titanium mesh material compared with the previous traditional material has been a big progress, however, it is not particularly ideal, there are still some problems. So which material is better for cranial bone repair? What are the advantages and disadvantages of titanium mesh? Compared to traditional materials, titanium mesh has its advantages; however, compared to the more advanced polyether ether ether ketone (PEEK) materials, the disadvantages of titanium mesh become apparent. Of course, one advantage of titanium mesh over PEEK is that it can be slightly less expensive. But its shortcomings are indeed many, such as titanium mesh is a metal material, higher thermal conductivity, thermal insulation is not good, which may cause a sensitive reaction to heat and cold; in addition, it may cause chronic pain, subcutaneous accumulation of fluid; this metal material will affect the future to do a variety of medical examinations, such as CT MRI ah, artifacts, resulting in diagnostic interferences; in addition, titanium mesh tensile lightness, stability, elasticity, etc. also have a larger Gap. Therefore, if conditions permit, it is recommended to do this kind of polyether ether ketone repair. We have used this advanced PEEK material to achieve good repair results, and have received favorable comments from patients all over the country.