Long-term bedridden patients, the following signs are generally found before death: First, the patient appears to be in a persistent lethargy, call can be answered, but can not be normal communication, the patient can quickly fall asleep again. Mainly because of the extreme lack of energy in the patient’s body, by keeping asleep, can reduce the consumption of energy. Second, the patient can’t eat by mouth, at this time the patient’s gastrointestinal function is very poor, there is no obvious hunger, can only be supplemented by intravenous infusion of energy. Third, monitor the patient’s blood pressure, heart rate is extremely unstable, oxygen saturation for a long time below 80%, suggesting that the patient’s internal environment is disturbed, and the body is in a state of extreme hypoxia. Fourth, the patient may have the manifestation of incontinence, mainly due to the loosening of the urethral and anal sphincter, urine and feces can be discharged by themselves.