If the glans is due to a fungal infection, treatment with clotrimazole cream is relatively effective. If the infection is caused by other pathogens, the effect of this drug is not ideal. Clotrimazole cream is a broad-spectrum antifungal drug, commonly used in the treatment of ringworm, tinea pedis, candida onychomycosis, candida vulvovaginitis and other diseases. If the patient’s glans is due to fungal infection, usually follow the doctor’s instructions for local use of clotrimazole cream can achieve the desired therapeutic effect, so as to alleviate the local itching, pain and other uncomfortable symptoms. If the patient’s glans is infected with Trichomonas vaginalis, Staphylococcus aureus and other pathogens caused by the application of clotrimazole cream treatment is not ideal, should be taken seriously. Some patients apply clotrimazole cream, occasionally see allergic reactions, erythema, edema and other adverse reactions, the contraindications are not clear, but should avoid applying to the eyes and other mucous membrane parts. It is recommended that patients with glansitis to clarify the cause of the disease, follow the doctor’s instructions to use medication, not to use clotrimazole cream on their own. If there is a burning sensation, redness and swelling at the site of application, the drug should be discontinued and the local skin should be rinsed with water, followed by medical treatment.