Charcot’s triad is also known as Charcot’s triad, which refers to the presence of three clinical manifestations, including abdominal pain, chills and high fever, and jaundice. It is a clinical symptom of cholangitis secondary to extrahepatic bile duct stones. The clinical manifestation of abdominal pain mainly occurs in the subglottis, right upper abdomen or epigastrium, mostly in the form of colic paroxysms. The pain may increase continuously and radiate to the right shoulder and back, and is accompanied by nausea and vomiting, chills and high fever. The abdominal pain is usually followed by chills and high fever due to the introduction of toxins from the infected bile ducts into the bloodstream, and may manifest clinically as yellowing of the skin and sclera due to bile duct inflammation and biliary system opacification. The presence of such a condition signals a more serious disease and should be accompanied by immediate anti-infective and anti-inflammatory treatment, along with support for symptomatic rehydration, and rapid relief of the obstruction, which can reduce inflammation and relieve chills and hyperthermia. If the Charcot triad is not corrected in time, it may develop into Charcot pentad, which may even endanger the patient’s life.