Menstrual leave generally has no effect on platelets, normal menstrual bleeding is 20-60mL at a time, which will not lead to anemia, and will not cause platelet changes. Unless the amount of menstruation is very large, resulting in excessive bleeding, causing anemia or coagulation dysfunction, it may have an effect on platelets. If the period is usually a normal one, it will not affect the platelets. If the amount of menstruation is relatively heavy, which is not normal, you need to actively find the cause, first of all, you need to do pelvic ultrasonography to see if there are uterine fibroids, uterine adenomyosis, endometrial polyps and other diseases, and if necessary, you need to be treated by surgery. If pathologic factors are excluded, simple thrombocytopenia may be related to immune factors.