In outpatient and ward work, when doctors propose to patients to treat with insulin according to their condition, they are often refused by the patients with the reason that once they are on insulin, they have to use it for the rest of their lives and cannot withdraw it! In fact, this is a misunderstanding of the use of insulin, or due to misinformation and mishearing. Insulin is just a normal hormone secreted by the beta cells of human pancreatic islets, a substance that is present in any normal human body, and it is impossible to become addicted to it. In fact, there are many patients who are just avoiding the disease and believe that using insulin means aggravation of the disease, so they wishfully believe that “insulin is addictive” and thus find an objective reason for refusing to use insulin. In 1985, the United Nations Health Organization recommended that diabetes be divided into insulin-dependent diabetes, which is type 1, and non-insulin-dependent diabetes, which is type 2. In fact, type 2 diabetes also requires insulin treatment when it progresses to pancreatic islet beta cell failure. Unlike type 1 diabetes, type 1 diabetic patients need insulin treatment from the beginning of the disease, while type 2 diabetic patients need insulin treatment only at the later stage of the disease when oral hypoglycemic drugs are effective at the beginning. As for the question of whether insulin can be withdrawn once it is used, it cannot be generalized. Some patients may recover the function of pancreatic beta cells to a certain extent after using insulin for 3-6 months (the doctrine of pancreatic beta cell rest), and then switch to oral hypoglycemic drugs may be effective at this time. However, in some patients, due to the depletion of pancreatic β-cells, insulin will no longer be effective for oral hypoglycemic drugs even after using insulin for a period of time (too late for use!). . The goal of diabetes treatment is to get good control of blood glucose (and of course blood lipids and blood pressure), and only when blood glucose is well controlled can complications be prevented or delayed. Once complications occur, they cost much more than when blood glucose is well controlled, and there is no specific treatment for many complications to date. Therefore, I suggest that diabetic patients, when the condition requires insulin therapy, please do not hesitate to accept it bravely!