The treatment of subpleural solid nodules needs to be combined with the nature of the nodule to choose general treatment, drug treatment, surgical treatment, etc., and the use of drugs should follow the doctor’s instructions. 1. General treatment: If the subpleural solid nodule is a scar proliferation foci caused by residual inflammation, it may exist forever. If there is no clinical symptom, no special treatment is needed, and regular review and observation of changes in the nodule is enough. 2. Medication: If the subpleural solid nodule is caused by inflammation, antibiotics such as cefaclor can be used for treatment, which may disappear gradually after a period of treatment. 3. Surgery: If the nodule is large and affects the respiratory function, or if the nodule is suspected to be malignant, surgery is recommended. When solid nodules are found under the pleura, it is suggested that patients should go to regular hospitals in time and be treated under the guidance of doctors instead of diagnosing and treating by themselves.