What to do when transaminases stay high in the decompensated phase of cirrhosis?

Elevated aminotransferase in the decompensated stage of cirrhosis indicates hepatocyte damage, and liver function can be improved by removing the etiologic factors, protecting hepatocytes, and maintaining enteral nutrition. 1. Remove the causes: Hepatitis virus and fatty liver disease are common causes of cirrhosis. Those caused by hepatitis B virus can be treated with anti-hepatitis B virus such as entecavir; those caused by hepatitis C virus can be treated with anti-hepatitis C virus drugs such as sofosbuvir; and steatohepatitis can be treated by controlling the diet, increasing exercise and other lifestyles. 2. Protect liver cells: when cholestasis occurs, minimally invasive surgery can be used to relieve biliary obstruction to avoid further damage to liver function. Ursodeoxycholic acid can also be taken orally to minimize the damage to liver cell membranes. 3. Maintenance of enteral nutrition: enteral nutrition is the best way for the body to obtain energy, which is important for the maintenance of liver function. At the same time, drugs that are damaging to the liver should be avoided to reduce the metabolic burden on the liver. Continuous elevation of aminotransferases indicates damage to liver cells, and it is recommended that the patient consult a doctor in time and follow the doctor’s instructions for proper treatment. Drugs need to be used under the guidance of a doctor.