Hypoproliferative leukemia is not easy to treat and the treatment is less effective. Hypoproliferative leukemia is a special type of leukemia that is relatively rare in clinical practice, and the common symptoms of patients include dizziness, shortness of breath, panic, pallor, fever and infection, and bleeding. Meanwhile, as the disease progresses, the typical symptoms of decreased white blood cells, hemoglobin, and platelets will appear. Hypoproliferative leukemia has a more insidious onset, is not easy to be detected, progresses slowly, and can have no obvious symptoms in the early stage, followed by the majority of middle-aged and old-aged patients, due to the poor hematopoietic function of the patients in this age group, the imbalance of the immune state, the conventional high-dose chemotherapy often can not be carried out, and therefore, the treatment effect is poorer. Specific therapeutic drugs include Azacitidine, Vinacrine, Cytarabine, Zoerythromycin and so on. The use of drugs needs to be under the guidance of a physician.