38.5 degrees never go down refers to a fever of 38.5 degrees never go down, which may be caused by inflammatory infections, lymphoma and systemic lupus erythematosus. 1. Respiratory tract infection: Due to weather changes or low immunity, viruses or bacteria invade the respiratory tract, causing localized inflammation of the respiratory tract or uncontrolled infection, which may result in a fever of 38.5 degrees that won’t go away. 2. Lymphoma: due to the poor immunity and resistance of lymphoma patients, there will be complications of infection and the infection damages the organism, which may lead to the situation that the fever of 38.5 degrees does not go down. 3. Systemic lupus erythematosus: due to the inflammation of the original disease itself, it will lead to the patient to have a fever of 38.5 degrees that does not go away. Patients with a fever of 38.5 degrees does not go away, it is recommended that patients go to the hospital in time to identify the cause of the disease, according to the cause of the standardized treatment.