Symptomatic paralytic syndrome is not a standardized medical name and may refer to paralytic dementia. It is a manifestation of advanced syphilis caused by the invasion of the brain by the syphilis spirochete, and the patient is mentally or physically impaired, characterized by neurological paralysis, progressive dementia, and personality disorders. Paralytic dementia is a chronic meningoencephalitis caused by the invasion of syphilis spirochetes into the brain parenchyma, which is the most serious type of neurosyphilis. 1. Mental aspect: early patients will have symptoms of neurasthenia, followed by intellectual decline, impaired understanding, analysis and judgment, and emotional instability. The mental disorders of patients in the developmental stage become more and more serious. In the late stage, there will be intentional inversion. 2. Physical aspects: including neurological symptoms, mostly occurring in the middle and late stages, the patient may experience sensory anomalies, pupils generally shrink, vision loss, etc., and may also be accompanied by speech and writing disorders, tremor, tendon reflexes abnormalities and other symptoms. If the above symptoms occur, it is recommended that the patient go to the hospital in time and receive targeted treatment under the guidance of a professional doctor.