There is no fastest and most effective way to open blood vessels. Clinically, commonly used medications to open blood vessels include aspirin, statins and other plaque-stabilizing drugs, as well as thrombolytic drugs such as alteplase, etc. A light diet, low salt and low fat, and a balanced and comprehensive nutritional profile are appropriate. 1. Aspirin can inhibit platelet aggregation and thus effectively prevent the occurrence and reoccurrence of vascular obstruction. However, it should be noted that it may cause bleeding, such as gastrointestinal bleeding. It is contraindicated in patients with active gastrointestinal ulcers, severe cardiac, hepatic or renal insufficiency, and pregnant women. Platelets need to be closely monitored while taking the drug. 2. Assuvastatin can prevent vascular blockage by lowering the blood lipid level in the body, thus delaying or preventing vascular lesions. However, you need to pay attention to adverse reactions such as gastrointestinal discomfort, headache and rash while taking the drug. It is contraindicated in women with active liver disease, severe renal insufficiency and pregnancy. Blood lipid level, liver and kidney function should be closely monitored during the period of taking the drug. 3. Thrombolytic drugs: such as alteplase, can dissolve blood clots to achieve the effect of vascularization. However, the application should always pay attention to intracranial hemorrhage and gastrointestinal bleeding and other adverse reactions. Patients with acute visceral bleeding, uncontrollable hypertension or acute intracranial hemorrhage are prohibited. Before application, patients should pay attention to whether platelets and coagulation five items are normal, and patients’ vital signs should be observed at all times when using the drug. If there is any discomfort, patients are advised not to take the drug by themselves, but should go to the regular hospital and follow the doctor’s instructions for treatment.