Whether bladder cancer patients can be vaccinated needs to be based on the immune system condition and physical condition, if the patient’s immune system is suppressed, low white blood cell level or physical condition deviation, etc. is not recommended to be vaccinated. Clinical vaccination requires good physical condition, no obvious wasting disease, no allergic disease and no history of vaccination allergy. Bladder cancer itself belongs to malignant tumor, which has obvious consumption to the body. If the patient’s physical condition is poor and there is immunocompromise, etc., vaccination is not recommended. If the patient receives radiotherapy and other treatments, it can cause bone marrow suppression, low white blood cells, impaired immune function, etc. Vaccination may lead to failure to produce antibodies or infections, etc., and it is easy to have adverse reactions, etc. When bladder cancer is found in clinic, it is necessary to consult doctor for observation in time, and carry out standardized treatment under the guidance of clinician after diagnosing the condition, so as to avoid delaying the condition. After recovering from the disease, the vaccine should be injected according to the doctor’s instruction.