Hormonal drugs, clinically generally referred to as glucocorticoid drugs, the best time to take them is usually between 7 and 8 o’clock. Glucocorticoid drugs, mainly prednisone acetate, dexamethasone, etc., its main role is to inhibit the body’s immune response, reduce inflammation, reduce the attack of the disease. Clinically used in allergic and autoimmune inflammatory diseases. The secretion of human glucocorticoid hormone is a circadian rhythmic change, the secretion peak is generally 7 to 8 o’clock in the morning, 2 to 3 o’clock in the afternoon and gradually decrease, the least secretion at night, so the best time to take glucocorticoid drug is generally between 7 to 8 o’clock, this time to take and the body’s own endogenous glucocorticoid secretion curve coincides with the body’s own, the impact on the human body is smaller. Prolonged application of glucocorticoids may cause adverse reactions such as elevated blood glucose, peptic ulcer, hypothalamic-pituitary-adrenal axis suppression, and concurrent infections. Contraindications are hypersensitivity to the components of the drug, fungal infections. Glucocorticoid drugs are recommended to be used under the guidance of a doctor, remember not to adjust the drug on your own, if there are any adverse reactions such as those mentioned above, you should consult a doctor in time and undergo treatment.