High EGFR refers to the increase of glomerular filtration rate, which indicates that the detoxification capacity of the kidney is enhanced. The kidney is an excretory organ, mainly responsible for drainage and excretion of toxins in the body, the detoxification capacity is within a certain range, normally at 80-120 ml/min, if it is close to 120 or more than 120, it is considered as increased glomerular filtration rate. An increased glomerular filtration rate is not a good sign, because a long-term increase in glomerular filtration rate will lead to a decrease in kidney function, which may eventually develop into renal failure. Therefore, when the glomerular filtration rate is elevated, we must actively look for the cause and deal with it from the etiology For example, in the early stage of diabetic nephropathy, the glomerular filtration rate is significantly elevated, which is manifested as high perfusion, high filtration and high pressure. In addition to treating the cause of elevated glomerular filtration rate, you can also use some drugs to temporarily reduce the glomerular filtration rate such as perindopril tablets, valsartan capsules and so on.