Lupus erythematosus accompanied by itching of the skin of the face is a symptom of some specific types of lupus erythematosus, such as acute generalized cutaneous lupus erythematosus and chronic cutaneous lupus erythematosus. It may also be associated with contact dermatitis. 1. Acute generalized cutaneous lupus erythematosus is one of the more common types of cutaneous lupus erythematosus, which is mainly manifested as symmetrically distributed small papules and blotches all over the body, accompanied by a certain degree of itching. 2. Chronic cutaneous lupus erythematosus with itching symptoms mainly includes discoid lupus erythematosus and linear lupus erythematosus. (1) Discoid lupus erythematosus is characterized by well-demarcated erythematous spots or plaques with adherent scales on the surface, and some people may experience mild itching. (2) Linear lupus erythematosus is an extremely rare special type, with lesions on the head and face, and subcutaneous nodules and erythema accompanied by itching. 3. Contact dermatitis is an allergic reaction due to local skin contact with some kind of irritating or sensitizing articles, which is mainly manifested as rash and itching in the clinic. Due to the many factors affecting it, the specific situation needs to be analyzed by a doctor’s consultation and in conjunction with the time of onset of the disease.