Chronic cystitis without a history of allergies can be increased by choosing to combine cephalosporin antibiotics such as cefaclor, cefuroxime, cefdinir or by combining it with fosfomycin aminoglutethimide. Chronic cystitis infectious disease is more common, the course of the disease is long, can be recurrent, the symptoms are bladder irritation symptoms: frequent urination, urinary urgency, painful urination. Cystitis is usually caused by a bacterial infection, the common bacteria is E. coli, so you need to choose a sensitive antibiotic. Ciprofloxacin is a quinolone antibiotic, which has good bactericidal effect on various common bacteria. However, due to the long course of chronic cystitis, it is easy to develop drug resistance, in order to enhance the efficacy of treatment can choose to combine drugs to enhance the antibacterial effect. For example, the choice of second-generation cephalosporin antibiotics are cefaclor and cefuroxime, and third-generation cephalosporin antibiotics are cefdinir and cefotaxime. You can also choose the fosfomycin aminotriol, which is very effective for urinary tract infections. Generally the course of treatment also needs to be longer requiring about 10-14 days. In addition, the patient needs to increase the amount of water intake, more urine, can play a self-purifying effect on the urinary system. As anti-infective drugs are prescription drugs, patients with chronic cystitis are best to actively seek medical treatment, the clinician to choose sensitive and appropriate antibiotics.