If treatment of osteoarthritis of the knee joint through warmth, exercise and physical therapy is ineffective, medication may be considered. The main drugs used to treat osteoarthritis of the knee are anti-inflammatory painkillers that improve symptoms and drugs that replenish cartilage components. Anti-inflammatory painkillers eliminate the inflammatory factors that stimulate synovial secretion and relieve joint pain. When it comes to anti-inflammatory painkillers there is another misconception, the people often think that painkillers are addictive when taken. In fact, anti-inflammatory painkillers are not addictive, but only opioid painkillers, such as morphine and dulcolax, can be addictive if taken in excess. Anti-inflammatory painkillers Anti-inflammatory painkillers are usually taken at the early stage of inflammation in the knee joint and continue to be taken for two to three weeks before the inflammatory factors in the joint become less and the joint swelling and pain is reduced. Some patients feel sick to their stomachs after using the medication, so they can switch to a medication that is less irritating to the gastrointestinal tract, or switch to an ointment, spray or patch that is absorbed through the skin to reduce irritation to the gastrointestinal tract. Aminoglucose In addition to anti-inflammatory and pain medications, you can also take aminoglucose, but some patients have results with it, while others have little or no effect. On the whole, taking glucosamine is effective because joint cartilage is not unchanged for life, the cells that make up joint cartilage are always in a dynamic balance of metabolism, and glucosamine is the nutrient that synthesizes cartilage cells. Taking glucosamine orally can improve the cartilage throughout the body, but it cannot cure it at all. Injections For patients who do not do well with oral medication or who have a significant joint effusion, there are two types of injections. One type is the injection of hormones into the knee cavity, which is useful for acute synovitis but only provides short-term relief. It is important to note that this should not be repeated within three months and up to three or four times a year. Too many hormone injections can instead accelerate the degeneration of joint cartilage. In addition, patients with osteoarthritis of the knee can also choose to inject sodium vitrate. Normal articular cartilage has no nerves, blood vessels or lymph, and relies mainly on joint fluid for nutrition and protection. Sodium vitrate, the main component of synovial fluid, can increase the amount of synovial fluid after injection, improve the viscosity and lubricating function of synovial fluid, and reduce the friction between joints; sodium vitrate can also dilute and inhibit the secretion of inflammatory factors by synovial membrane, relieve pain and increase the mobility of joints. In clinical practice, I apply small needle knife to regulate the knee joint and overall force balance, improve blood circulation, and promote the recovery of the body can obtain satisfactory long-term results. A large amount of clinical data can be confirmed.