Auntie Yuan, aged 10, has suffered from rheumatoid arthritis for more than 10 years and has been taking chloroquine drugs for treatment. In recent years she began to feel blurred vision, dry and red eyes, and even photophobia and stinging pain. A series of tests were done on this patient, including visual acuity, optometry, slit lamp microscopy, tear secretion test, fluorescein staining, intraocular pressure, and an exhaustive fundus examination, among others. She was found to have a corrected visual acuity of 0.4 in both eyes and was suffering from dry eye disease, superficial scleritis and cataracts, all of which are closely related to rheumatoid arthritis. Rheumatoid arthritis is a chronic systemic autoimmune disease with mainly joint lesions, which can have pathological changes in many organ systems throughout the body. The eye is an organ of rheumatoid disease with lesions outside the joints, and often some lesions occur, such as sclerositis, keratitis, corneal ulcer, cataract, iridocyclitis, choroiditis, ischemic optic neuropathy, strabismus, etc., which may develop to blindness in severe cases. Dry eye disease is the most common eye disorder in patients with chorioretinopathy. Dry eye disease means that the tear glands do not secrete enough tears or the tears secreted do not effectively stay on the surface of the eye, so that the eye loses its surface layer of protective film, which can easily cause dryness, inflammation, infection, and even ulcers on the surface of the eye. The patient’s eyes are dry, itchy, photophobic, prone to tearing, and sore and uncomfortable as if sand had been blown into the eye. There is also eyelid heaviness and difficulty in opening, eye fatigue, which is aggravated at night or when reading, and eye discharge sticking to the upper and lower eyelids when waking up in the morning. Many of these patients have been treated inappropriately for what is thought to be “trachoma” and their symptoms have not improved or have even worsened. Mild cases should be controlled with artificial tear replacement therapy, while moderate to severe cases of dry eye can be treated with oral medications to promote tear production, tear plugs or salivary gland transplantation. Sclerositis is commonly known as inflammation of the “white” of the eye, and can be classified as superficial sclerositis, sclerositis, and simple sclerositis, nodular sclerositis, necrotizing sclerositis, etc. according to the location. Mild sclerositis will have localized congestion, pain or no significant pain in the eye. Severe sclerositis can cause the wall of the eye to become very thin, gradually soften, or even perforate. Treatment of scleralgia requires hormones or immunosuppressants, and recurrent attacks may occur after a single cure. However, control of the disease itself is very important for sclerochoroiditis, which can be very persistent if the sclerochoroid is still active. The corneal ulcers associated with S. cerevisiae tend to occur at the edge of the junction between the cornea and the sclera, and in severe cases, ulcers can occur all along the edge of the cornea leading to corneal perforation and blindness. This ulcer is an aseptic corneal meltdown that is associated with an autoimmune response. However, it is not uncommon for corneal ulcers to be clinically misdiagnosed as infectious. The author has seen many patients who were mistakenly treated with antibiotics for this disease and came in with late stage or perforation, and were only able to save their vision and eyes with repair and local application of hormones, immunosuppressive drugs, etc. Cataracts occur earlier and progress more rapidly in patients with carcinoid off. Such cataracts are related to a variety of factors, such as eye inflammation, the use of topical hormonal eye drops, the use of systemic medications, and so on. The effective treatment for cataracts is surgery. The current commercially available eye drops for cataracts cannot stop or reverse the development of cataracts. For cataracts that have not yet significantly affected vision, surgery can be suspended. At the same time, when there are other eye diseases related to cataracts, such as severe dry eye disease, scleritis, and uveitis, surgery should not be performed until the inflammation has been controlled by medication. At present, the cataract surgery method that has been widely carried out at home and abroad is ultrasonic cataract extraction, which requires only eye surface anesthetic drops to complete the preoperative anesthesia, a small incision (the diameter of the incision can be as low as 2mm or less), little trauma, and short time (a skilled surgeon can complete the entire surgery in 10 minutes), and then implant different kinds of IOLs according to the patient’s different needs. There is a wide variety of IOLs available, such as multifocal IOLs and UV-protected IOLs, which allow for a great improvement in visual comfort for patients. The uvea is the middle structure of the eye wall, so named because of its richness in blood vessels and dark brown color. This area is a favored site for immune reactions, and uveitis is often associated in patients with immune system-related diseases. Iridocyclitis (iridocyclitis for short) is an anterior uveitis and is very common in patients with rheumatoid arthritis, which presents with red, painful eyes, photophobia, and decreased vision. It should not be confused with conjunctivitis, which requires pupil dilation and treatment to suppress the immune response. If misdiagnosed as conjunctivitis and given ordinary anti-infective eye drops, the condition will be delayed and, in severe cases, secondary to cataracts and glaucoma, which will need to be treated by surgery at the appropriate time. In addition, many drugs used to treat wind-like disease are toxic to the eyes, and chloroquine is one of them. People who take chloroquine for years will have deposits of chloroquine substances in many tissues of the eyes, such as the cornea and retina. The development of the lesions that cause vision loss will not stop when the chloroquine is stopped, and the fundus examination can reveal abnormal changes such as bullous macular degeneration. Therefore it is very important for patients to visit their specialist for regular follow-up. Such drugs also include non-steroidal anti-inflammatory drugs, glucocorticoids, gold agents, methotrexate, penicillamine, etc. Non-steroidal anti-inflammatory drugs can cause corneal and optic nerve toxicity; long-term use of glucocorticoid therapy can cause cataracts and glaucoma; gold preparations are the main adverse effects of the systemic gold deposits in many parts of the body, but also in the cornea, conjunctiva, lens, but also can cause extraocular muscle paralysis; methotrexate can be secreted with the tear, causing corneal conjunctival toxicity; penicillamine can cause immune dysfunction, causing optic nerve The disease is caused by penicillamine. For Yuan’s condition, we treated her with cataract ultrasound emulsion extraction combined with aspheric IOL implantation after several months of dry eye and sclerositis treatment with relevant medications, and her vision was restored to 0.8 with no other discomfort. In conclusion, the eye is a very important part of the human body, and treatment of systemic diseases should not be neglected while treating ocular disorders, otherwise the patient’s visual function may be seriously jeopardized. For patients with rheumatoid arthritis, internal medicine physicians and ophthalmology specialists should collaborate in the treatment.