Stomach pain always occurs in the middle of the night, mostly related to duodenal ulcer and gastric ulcer. Duodenal ulcer patients, because of the usual stress, diet eat not easy to digest food, long-term this leads to the gastric mucosa by a certain amount of stimulation damage. Long-term inflammation in the middle, often in the hunger will appear stomach pain, because by the middle of the night when the body has eaten the food has been digested, almost empty stomach. Empty stomach has a lot of gastric juice, because there is no food and gastric juice mixed directly into the duodenum, gastric acid stimulation of the ulcer surface will cause bursts of pain. If the gastric ulcer patients, in the middle of the night when the stomach is empty, the stomach is also secreted a lot of gastric juice, too much gastric acid to stimulate the ulcer surface, so cause the middle of the night stomach pain, after eating food pain will be relieved.