The causes of osteochondritis include pathogenic infection, chronic strain injury, and tumor tissue invasion. Pathogen infection, an infection in a part of the body or an infection caused by trauma, causes pathogens to enter the bloodstream and spread to the periosteum, resulting in osteochondritis dissecans. For patients with infectious periostitis, if bacterial infection is suspected, they can be treated with broad-spectrum antibiotics, and then corresponding antibiotic treatment based on bacterial culture or drug sensitivity test. Chronic strain injury, is due to the usual low activity, suddenly one day to increase the amount of exercise, it is easy to cause the muscle long time in a state of tension, the bones, muscles repeatedly exert external force action, the corresponding periosteum and periosteal blood vessels appear tear, hematoma and inflammatory changes. Tumor tissue invasion, due to malignant tumor tissue metastasis, invades the periosteal tissue and produces periosteal inflammation. For periostitis invaded by tumor tissue, timely and clear diagnosis, timely and effective comprehensive treatment. Osteochondritis dissecans may also have other causes, it is recommended to go to the hospital in time, improve the examination to clarify the cause of the disease, and then give targeted treatment or therapy.