What is advanced age? In medicine, women who are 35 years old at the time of delivery are called “advanced maternal age”. In general, women’s bodies gradually age after the age of 35, as follows: 1) Ovarian function decreases, egg quality deteriorates, and the probability of chromosomal abnormalities in eggs increases. 2. Menopause is approaching and menstrual cycles are gradually becoming irregular. 3. Vaginal secretions become more viscous, which is not conducive to the passage of sperm. 4. The endometrium becomes thinner, making it difficult for a fertilized egg to settle. 5. The pelvis, ligaments and muscles become less elastic and physically weak. 6. Reproductive system diseases (e.g. endometriosis, polycystic ovary syndrome, etc.), and other system diseases (e.g. diabetes, hypertension, etc.), gradually become more prominent in terms of their impact on fertility. Male spermatozoa are differentiated from spermatogenic stem cells in the testes, and in theory – men can produce sperm throughout their lives. However, as men age, their germ cell chromosomal aberrations and mutations increase, with the sperm DNA fragmentation index being three times higher in men aged 36-57 years than in men under 35 years. Advanced age is associated with the following: 1. increased likelihood of infertility 2. increased rate of miscarriage 3. increased risk of pregnancy Women of advanced age are prone to high blood pressure and diabetes when pregnant, and these diseases also pose a risk to pregnancy. However, a study has shown that women over 40 are less likely to develop hypertension during pregnancy than younger women, as long as they are not overweight. According to relevant statistics, the incidence of gestational hypertension syndrome in older primiparous women is about five times higher than in younger primiparous women. 4, delivery difficulties 5, embryonic malformations increased probability From the above, it is clear that the risks of advanced age are diverse. Therefore, it is more important to take good care of yourself and your baby in advanced maternal age.