Hand and foot ulcers after taking oral chemotherapy drugs usually need to be stopped. Hand and foot ulcers after taking oral chemotherapy drugs may be due to hand and foot syndrome caused by the chemotherapy drugs. Mild hand-foot syndrome is usually characterized by dullness of sensation, abnormal sensation or tingling sensation in the hands and feet, and if the allergic reaction is severe it may lead to peeling, ulceration, blistering and severe pain. When patients develop ulcers on their hands and feet, it is usually necessary to adjust the dose of chemotherapy drugs, lengthen the time between doses, and in more severe cases, stop the drugs. Avoid causing symptoms to become more severe. Oral chemotherapy drugs must be guided by a doctor, the patient can not use the drug at will, if the adverse reaction is more obvious, you need to stop the drug and consult a doctor, under the guidance of a physician to take other chemotherapy drugs or treatment methods.