The main cause of red hands and feet after taking nifedipine is vasodilation. Nifedipine is a commonly used clinical antihypertensive drug. It belongs to calcium ion in-flow blocker or slow channel blocker, which can block calcium ions from entering the cell through the channels of cardiac muscle or vascular smooth muscle cell membrane. It can play the role of relaxing vascular smooth muscle, dilating coronary arteries, and reducing peripheral vascular resistance, so as to achieve the purpose of lowering blood pressure. So patients may have red hands and feet after taking nifedipine. Redness of hands and feet after taking nifedipine occurs in patients who take this medicine for the first time. This is because after taking this drug for the first time, the sympathetic nerves become reflexively excited, which increases the vasodilating effect of this drug, and not only will the face be flushed, but also the hands and feet will be red. But this does not mean that patients can not continue to use this drug, as long as the patient can tolerate, or can continue to use. Patients must use nifedipine cautiously under the guidance of a professional doctor according to their specific situation, and never use the drug privately.