Coughing up sputum with blood may be caused by factors such as tuberculosis, bronchial dilatation, lung tumors, etc. It needs to be treated with anti-tuberculosis, anti-infection and surgery according to the cause of the disease. 1. Tuberculosis: when the patient has tuberculosis, the local lung tissue will produce caseous necrosis, thus bleeding, resulting in blood in sputum, at this time, you need to use rifampicin, ethambutol and other drugs for treatment. 2. Bronchial dilatation: When patients have bronchial dilatation, the walls of the bronchial tubes are thickened and small blood vessels are exposed. With coughing, the small blood vessels will bleed, resulting in sputum with blood, at this time you need to use phlegm drugs such as acetylcysteine and other drugs, such as accompanied by infection should also be used in cephalosporin and other drugs for anti-infection treatment. 3. Lung tumors: when patients have lung tumors, they need to be treated according to the pathological type and stage of the tumors, including surgical resection, radiotherapy and other methods. When the patient has blood in sputum, it may be caused by other reasons, and it is recommended that the patient should consult the doctor in time, make a clear diagnosis, and carry out standardized treatment to prevent the condition from being delayed.