Graves’ disease, also known as diffuse goiter with hyperthyroidism, is a systemic disease with typical clinical manifestations of hypermetabolic syndrome, goiter, and ocular symptoms.The ocular symptoms of Graves’ disease, also known as Graves’ ophthalmopathy, include the following: a. Eyelid contracture, which is more common in the upper eyelid and is characterized by enlarged lid fissures and exposure of the upper sclera . The upper eyelid does not move downward with the eye when the eye looks downward, and the eyes are shiny and transient. Second, protrusion of the eyeballs, unilateral or bilateral protrusion, can appear as diplopia, eye congestion, edema, and other symptoms. Graves’ ophthalmopathy can occur at the same time as hyperthyroidism, or after hyperthyroidism, and in a few patients it may even occur before the onset of hyperthyroidism.