Most of the chemotherapy and radiotherapy for moderately differentiated gallbladder cancer and mucinous adenocarcinoma are ineffective, so surgery is needed, and different surgical methods should be chosen according to the staging, and the commonly used surgical methods include simple cholecystectomy, radical resection for gallbladder cancer, extended radical surgery for gallbladder cancer, and palliative surgery. 1. Simple cholecystectomy: this type is mostly found by chance after cholecystectomy for gallbladder stones or cholecystitis, and the tumor is confined to the gallbladder and does not invade the muscular layer, so there is no need to perform surgery again after discovery. 2. Radical resection for gallbladder cancer: if the tumor has penetrated the plasma membrane and invaded the liver or other neighboring organs, the operation needs to remove the gallbladder and the corresponding liver tissues and do the surrounding lymph node dissection. 3. Extended radical surgery for gallbladder cancer: if the tumor has invaded portal vein or hepatic artery, or two or more neighboring organs, the surgery needs to remove most of the liver tissues, and even the liver, pancreas and duodenum if necessary. 4. Palliative surgery: for patients who are difficult to tolerate surgery or cannot remove gallbladder cancer, hepaticojejunostomy and gastrojejunostomy are commonly used. This operation can only relieve the obstruction symptoms caused by tumor. Gallbladder cancer has a high degree of malignancy, once found, it should be treated actively so as to avoid disease progression and adverse consequences.