There is no best treatment for cold knees, and you should actively find out the cause and treat it. Generally, it is caused by environmental changes, poor blood circulation, bone and joints, etc. The treatment methods include local warming, physical therapy, medication and so on. 1. Local warmth: knee cold is mainly due to daily not pay attention to the knee warmth, resulting in knee joint internal cold caused by soft tissue spasm or edema. It is recommended to pay attention to the warmth of the knee, can wear knee pads, do not let the knee exposed to the cold. 2. Physiotherapy: Cold knees may be caused by poor blood circulation in the lower limbs. It is recommended to promote blood circulation through hot compresses, massages, infrared rays and other physiotherapy methods. 3. Medication: Cool knees can also be caused by osteoarthritis, which can be treated with non-steroidal anti-inflammatory and analgesic drugs such as ibuprofen tablets, acetaminophen tablets and diclofenac sodium as prescribed by the doctor. Daily to avoid joint wear and tear, maintain a balanced diet, pay attention to the knee warmth, if the knee is cold, accompanied by other symptoms of discomfort, it is recommended to go to the hospital in time for examination.