The site of easy recurrence of colon cancer after surgery is the liver. The metastatic pathways of colon cancer include bloodstream metastasis, lymphatic metastasis, and implantation metastasis. Since the blood from colon returns to liver by portal vein, liver becomes the most likely site of colon cancer metastasis. About 50%-70% of colon cancer patients may develop liver metastasis, half of them have already occurred at the time of initial diagnosis, and half of them have liver metastasis occurring after surgery. Surgery is the best treatment for postoperative recurrence of colon cancer. If the number, size and location of metastatic foci can be completely resected, surgical treatment is usually adopted. If surgery is not possible, systemic chemotherapy or local radiotherapy can be adopted. Doctors need to evaluate the patient’s condition so as to adopt the best treatment plan.