Negative pressure replacement therapy in ENT is mainly for the treatment of chronic sinusitis, mainly anti-inflammatory drugs are injected into the sinus cavity through the replacement method, and then the purulent secretions inside the sinuses are cleaned out to achieve the effect of local anti-inflammatory. Generally, when patients suffer from chronic sinusitis, there will be a large amount of purulent secretions accumulating in the sinuses, because the mucous membrane in the nasal cavity is stimulated by inflammation, leading to edema, resulting in blockage of the sinus openings, and the patient will experience varying degrees of dizziness and a feeling of tightness and swelling in the head. In the use of this replacement method, the first need to use vasoconstrictive drugs, such as the choice of nasal drops, can make the mucous membrane of the nasal cavity contraction, so that the sinus opening, and then through the replacement method, the drug injected into the sinuses, can directly act on the affected area, can play an anti-inflammatory effect, in the auxiliary treatment is recommended to use saline or physiological seawater for nasal irrigation, but also help the disease of the Recovery.