The interval between doses is related to the type of medication and it is recommended to follow the instructions or medical advice, such as 12 hours between doses for 2 times a day medication and 8 hours between doses for 3 times a day medication. Each medication has a corresponding dosing interval and the physician will decide the dosing interval to maximize the efficacy of the medication based on the patient’s condition. For over-the-counter medications, patients can take them according to the instructions, 12 hours apart if they are recommended to be taken twice a day, 8 hours apart if they need to be taken three times a day, and so on. For prescription drugs, the time interval between doses should be determined according to the patient’s condition, and even certain drugs need to be taken at specific times, such as hypoglycemic drugs and antihypertensive drugs. When taking medications, the prescribed dosage and number of doses should be followed in order to avoid poor efficacy or side effects.