Hepatopathic appearance is mostly seen in patients with chronic hepatitis and cirrhosis, and is one of the common clinical manifestations in patients with liver disease. The hepatopathic appearance is mostly characterized by dry skin, dark and dull face. Some patients may also have hyperpigmentation of the face and other exposed areas of the skin, especially around the eyes. Differential diagnosis of hepatomegaly: Other life factors can also lead to phenomena such as darkening of the face, such as lack of sleep and malnutrition. There are also other diseases caused by reduced blood oxygen levels, such as pneumonia, high altitude, heart failure, asthma, pulmonary heart disease, constipation, and abdominal pain and diarrhea can cause it. There are also kidney diseases that often cause darkening of the face, as well as excessive fatigue, and people who are born with dark skin. All of these should be identified in the diagnosis.