Many people think that GERD is also a gastric disease, so is it a matter of getting well? Many friends confuse gastric disease with GERD, but in fact gastric disease is a variety of lesions that occur inside the stomach cavity, such as gastritis and gastric ulcers. Because GERD is also often manifested as heartburn and other symptoms, many people feel that it is still a disease of the stomach, so if you adjust your diet, eat less and rest, will you get better? In fact, the root cause of GERD is the esophagus. In normal people, there is a sphincter at the lower end of the esophagus that prevents the reflux of stomach contents into the esophagus, but in some people, the sphincter at the lower end of the esophagus becomes loose for various reasons, and this is the root cause of GERD. When this muscle becomes relaxed, the contents of the stomach will reflux into the esophagus when the patient is lying down or lying prone. Because the contents of the stomach are mainly acidic, and the esophagus is originally an alkaline environment, a large amount of acidic contents refluxed into the esophagus will stimulate the esophageal mucosa, and over time, reflux esophagitis is formed, and patients will show heartburn, belching, and some patients will have chest pain. If the esophageal mucosa is repeatedly stimulated by acid, Barrett’s esophagus (normal esophagus is squamous epithelium, if it becomes columnar epithelium, it is called Barrett’s esophagus), which is a precancerous lesion of esophageal cancer. In conclusion, the etiology of GERD is the relaxation of esophageal sphincter, which is not well nourished by simple nourishment and requires pharmacological treatment and surgical intervention.