Peri-anal eczema: Peri-anal eczema is confined to the skin around the anus and can rarely involve the perineum. It is unbearably itchy. It is often moist, with thickened infiltrated skin that can become cracked. It can develop at any age. Causes: The causes of eczema are complex, with the interaction of intrinsic and extrinsic factors, and are often multifaceted. External factors such as living environment and climatic conditions can affect the occurrence of eczema. External stimuli such as sunlight, ultraviolet rays, cold, heat, dryness, sweating, scratching, friction and various animal fur, plants, chemicals, etc., some daily necessities such as balsam and other cosmetics, soap, artificial fibers, etc. can induce eczema. Certain foods can also make eczema worse in some people. Intrinsic factors such as chronic digestive diseases, gastrointestinal dysfunction, mental stress, insomnia, mental changes such as excessive fatigue, infectious lesions, metabolic disorders and endocrine dysfunction can all produce or aggravate eczema. Clinical manifestations: confined to the skin around the anus, a few may involve the perineum. It is unbearably itchy. The skin is often moist, infiltrated and thickened, and may become chapped. In the acute phase, the rash is mostly dense, corn-sized papules, papules or small blisters with a flushed base. As a result of scratching, the lesions may show obvious punctate exudate and small vesicular surface, the center of the lesion is often heavier, and gradually spread to the surrounding, peripheral and scattered papules, papules, so the boundary is unclear. When combined with infection, the inflammation can be more pronounced and form pustules with pus oozing or yellow-green or dirty brown scabs. It can also be combined with folliculitis, boils, local lymphadenitis, etc. Treatment: 1. General treatment: (1) As far as possible to find the cause of the disease, so the patient’s work environment, habits, diet, hobbies and emotions, and a thorough examination of the general condition, the presence of chronic lesions and visceral organ disease, in order to remove possible causative factors. (2) Avoid all kinds of external stimuli, such as hot water scalding, violent scratching, excessive washing and other substances that are sensitive to the patient, such as fur products. (3) Avoid allergenic and irritating foods, such as fish, shrimp, strong tea, coffee, alcohol, etc. (4) Give a detailed explanation to the patient on the main points of protection, guide the medication, make cooperation with medical personnel, and give full play to the patient’s subjective initiative. 2, drug treatment: Western medicine can be used antihistamines to stop itching. In acute or subacute generalized eczema, 5% calcium bromide, 10% calcium gluconate or 10% sodium thiosulfate solution can be injected intravenously once a day, 10 times as a course of treatment. For those with widespread infection with the application of effective antibiotic treatment. In addition, vitamin B, vitamin C, and drugs that regulate nerve function are also helpful. One point worth noting is that glucocorticoids are not recommended. Although hormones have a quicker effect on anti-inflammatory, anti-itching and reducing exudation, they relapse soon after discontinuation and long-term application is prone to many adverse reactions.