Thyroid stimulating hormone (TSH) high how much need to take drugs should be combined with other tests to determine. If T3, T4 is normal, TSH<10μIU/mL usually do not need to take medication for the time being, TSH more than 10μIU/mL is usually treated with medication; if there is hypothyroidism, preparation for pregnancy, pregnancy and other conditions, TSH is high usually need to take medication. Consult your doctor for details. 1. T3, T4 is normal: TSH is high but T3, T4 is normal, which is generally subclinical hypothyroidism. If the TSH<10μIU/m, usually do not need to take medication for the time being, regular rechecking of thyroid function can be; TSH more than 10μIU/mL generally need to be treated with medication. Different hospitals may have different reference ranges. 2. T3, T4 abnormalities: that is, hypothyroidism, at this time, usually take levothyroid hormone as a replacement therapy. 3. Others: Preparation for pregnancy, pregnancy, combined with dyslipidemia or atherosclerotic disease, etc. If TSH is high, medication may be needed. If you have a high TSH, you should consult a doctor in time for evaluation of your condition and appropriate treatment under the doctor’s guidance.