Women are born with an inseparable relationship with endocrine and are more sensitive to endocrine changes than men at all stages of life and are prone to endocrine disorders, so they need extra care. In modern society, women, like men, are responsible for social and family burdens, and they also have to bear the additional burden of bearing and raising children. The alternation of life cycles and the pressure of work first manifest themselves in endocrine abnormalities, such as female development, childbirth and aging, abnormal fetal sexual development, precocious puberty, personality changes during adolescence, changes in appearance, skin changes, polycystic ovary syndrome, menstrual cycle, and endocrine disorders. The endocrine disorders are closely related to endocrine disorders, such as abnormal sexual development in fetus, precocious puberty in children, personality changes, appearance changes, skin changes, polycystic ovary syndrome, menstrual cycle changes, obesity in middle age, estrogen deficiency and osteoporosis. Endocrine disorders in childhood are not uncommon, and the earlier they are detected, the better the treatment effect, such as precocious puberty in women, hermaphroditism, abnormal obesity in children, cretinism, dwarfism, acanthosis nigricans, etc. All of them need timely medical consultation and early treatment. However, there are some diseases, especially hereditary diseases, that still lack effective treatment. The ovaries are one of the major endocrine organs of women, and their function determines female growth, development, fertility and aging, and is also closely related to a woman’s personality, beauty and physical longevity. At birth, there are approximately 2 million follicles in the ovaries. Before puberty, follicles begin to develop due to the action of pituitary gonadotropins, and after sexual maturity, one follicle per month matures, ovulates and forms the corpus luteum. During this process, the ovaries synthesize and secrete a variety of hormones, including estrogen, progesterone, and androgens, and the levels of these hormones change cyclically to form the regular menstrual cycle in women. Many common female problems, such as personality changes (irritability, isolation, depression); general discomfort (breast pain, abdominal heaviness, eyelid and ankle edema, insomnia, migraine, joint pain, facial sores, etc.), are mostly caused by abnormal hormone secretion and imbalance between estrogen and progesterone levels during the menstrual cycle, which has its physiological basis and is not simply a psychological factor. Menstruating women are very concerned about their appearance, body shape and want to have a gentle personality. They should pay more attention to the endocrine balance, such as thyroid hormone problems and ovarian function problems. Polycystic ovary syndrome is a more common endocrine syndrome in women of reproductive age, due to excess androgens or hyperinsulinemia. Common manifestations include scanty menstruation, amenorrhea, infertility, facial acne, hirsutism, obesity, insulin resistance and cystic deposits in the ovaries. Thyroid disease is also a common female endocrine disorder that manifests itself in various stages, such as adolescent goiter, Choban’s disease, postpartum thyroiditis, subacute thyroiditis, hyper- and hypothyroidism, and thyroid nodules, often afflicting women of all age groups. Hyperthyroidism may manifest as fear of heat, sweating, panic attacks, irritability, scanty menstruation, prolonged menstrual cycle, amenorrhea, and miscarriage. Hypothyroidism may manifest as chilliness, constipation, hair loss, excessive menstruation, prolonged menstrual cycle and infertility. These require timely detection and reasonable treatment. Adrenal gland disorders can lead to excessive androgen production, causing a range of masculine manifestations in women. Female patients with severe congenital adrenal hyperplasia are mistaken for males at birth because their vulva resembles that of a boy. Patients with late onset or mild form of the disease develop dense hair, scanty menstruation, prolonged menstrual cycles, amenorrhea, and infertility in adulthood. In addition to the above-mentioned androgen overproduction, Cushing’s syndrome is also associated with obesity, hypertension, osteoporosis, and purple skin lesions. In women, pituitary prolactinomas are commonly associated with obesity, overflow of breast milk, amenorrhea, infertility or miscarriage. Other causes of decreased pituitary function can also cause menstrual disorders. Pituitary growth hormone tumors can cause gigantism during development and acromegaly during adulthood, causing changes in appearance, both of which can be alleviated and cured if detected promptly. The period before and after menopause is called perimenopause, also known as menopause. Due to the decrease of ovarian hormone levels in the body, irritability, insomnia, redness, hot flashes, facial discoloration, bone and joint pain, which is often referred to as menopause syndrome, may occur. During this stage, it can bring inconvenience in life and conflicts in work and family. Women during this period need more care and treatment rather than avoidance and blame. After menopause, due to the continuous lack of estrogen, osteoporosis will quietly occur and progress. Bone and joint pain, shortening of height and hunchback are common symptoms in older women, and sometimes it is difficult to correct them by diet and calcium supplementation alone, therefore, systematic treatment and necessary endocrine replacement therapy are more important than in men. Female endocrine dysfunction is a common disease in endocrinology, which not only affects women’s health and life, but also affects women’s psychology and appearance, therefore, female endocrine regulation is also an important part of beauty care. The essence is to regulate the endocrine secretion and achieve the balance of hormones in the body, in order to truly show the charm and gentle character of women. Women with symptoms should seek medical attention early to clarify the cause and timely treatment to be a healthy and perfect woman.