Hands are full of holes like honeycomb may be due to eczema, sweat herpes and other factors. 1. eczema: generally believed to be due to a combination of internal and external factors, the acute phase of the herpes mound, with a tendency to ooze, commonly found in the face, ears, hands and other exposed parts of the face, the performance of the erythema on the basis of the emergence of corn-sized papules, pimples, blisters, can be fused into a piece, the boundary is not clear, and often because of scratching to form a pitting vesicular surface. 2. Sweat herpes: may be related to personal constitution, vegetative nervous system dysfunction, mental tension and other factors, seasonal episodes, summer, common in both hands on the side of the fingers, partially involved in the palm of the hand, fingers, and other parts of the end of the section, the performance of the deep in the blisters, slightly higher than the skin surface, surrounded by redness, often accompanied by sweaty hands and feet, itchy feeling or burning sensation, scratching may be vesiculoblasts, such as a honeycomb. Hands are full of holes like honeycomb may also be due to other factors, such as ringworm, palmoplantar pustulosis, etc., need to carry out the relevant examination, it is recommended that the patient timely medical treatment, under the guidance of the doctor to carry out the relevant examination, in order to clarify the cause of the symptomatic treatment.