Case sharing: Mr. Liu, 86 years old, started to have recurrent symptoms of cough and shortness of breath two years ago, which gradually worsened with dyspnea, and was referred to our hospital (Coal General Hospital). Chest CT examination showed right lung atelectasis. Bronchoscopy showed a spherical neoplasm in the right main bronchus, which almost completely blocked the right main bronchus, and pathologic biopsy showed squamous carcinoma. Based on the microscopic findings and chest CT, it was considered that the lesion originated from the right upper lobe. Due to the large size of the lesion, most of the tumor was resected by lancing with an electric coiler, and then the local area was treated with argon gas knife, and the patient’s dyspnea was significantly relieved after the operation. One course of radiotherapy was performed after surgery. Six months later, bronchoscopy review, the right main bronchus new organisms, again argon knife treatment, the lumen is clear after treatment, follow-up one year did not see recurrence. Argon knife treatment is an effective method for the treatment of solid tumors in the airway. With immediate effect, it can not only treat central type bronchial lung cancer, but also make the tissues in the airway coagulate and necrosis and vaporize; small tumors can be removed and large tumors can be shrunk to stop or slow down their spread, so as to relieve a series of symptoms such as dyspnea, fever, obstructive pneumonia and hemorrhage caused by airway obstruction. It can also selectively kill tumor cells and enhance the anti-tumor effect of chemotherapy and radiotherapy and the anti-tumor immune effect of the host. Spherical neoplasm of the right main bronchus, which almost completely blocked the lumen Performed electrocoil device ligation to remove part of the tumor Performed argon knife treatment on the lesion After treatment, most of the tumor was seen to be cleared from the lumen