The good thing about taking Sacuba (Sacubitril valsartan sodium tablets) is that it helps to reduce the risk of cardiovascular death and hospitalization because of heart failure, and the bad thing about it is that you may experience adverse effects such as angioedema and hypotension after taking the drug. Sacubitril valsartan sodium tablets, which are used primarily in adult patients with chronic heart failure who have reduced ejection fraction, help reduce the risk of cardiovascular death and hospitalization due to heart failure in patients, and can be used in place of angiotensin-converting enzyme inhibitors or angiotensin II receptor antagonists, in combination with other anti-heart failure medications. Adverse reactions such as angioedema, hypotension, renal impairment, hyperkalemia, and hepatic impairment may occur after administration of this product, and application of this product in pregnant women may cause fetal damage, decrease fetal renal function and increase fetal and neonatal morbidity and mortality. This product is contraindicated in those who are allergic to the active ingredients (sacubitril, valsartan) or any excipients of this product; prohibited from combining with angiotensin-converting enzyme inhibitors; contraindicated in patients with hereditary or idiopathic angioedema; contraindicated in patients with severe hepatic impairment, biliary cirrhosis and cholestasis; contraindicated in patients with mid- and late-stage pregnancies and so on. Drugs should be used in accordance with medical advice.