Extrapyramidal reactions refer to the excitatory effect of the extrapyramidal system under the influence of external causes and lead to its dysregulation by the central nervous system and other control, so that the excitability of the extrapyramidal system is increased, and a series of symptoms and signs related to muscle strength and muscle tone are triggered. There are four main clinical manifestations: first, inability to sit still, mainly manifested by walking back and forth, depressed, anxious or unpleasant, uncontrollable and other behaviors. Second, acute dystonia, manifested as local muscle groups and other persistent forced contraction, involuntary and other bizarre performance, such as slanting neck, neck back, eye roll up, etc.. Third, delayed dyskinesia, rhythmic involuntary stereotyped movements. Fourth, Parkinson’s syndrome, high muscle tone, tremor, motor inability, autonomic dysfunction, and in severe cases, loss of coordinated movement, panic gait, rigidity, mask face, salivation, etc.