Diabetes is actually bundled with other diseases and is a component among a collection of multiple diseases, not just a simple matter of elevated blood sugar. These components include obesity, hypertension, dyslipidemia, hyperuricemia or gout, and each of their members is causative and mutually reinforcing, creating a vicious cycle of dynamics. They can appear individually and successively, playing the role of a solo comic, or they can appear simultaneously in different combinations or collectively. In the latter case, the power of this combination is not a matter of 1+1=2, and the danger to human health must not be underestimated. Therefore, for diabetic patients, the above aspects should be taken into account in a comprehensive examination at least once or twice a year, and for those with poorly controlled disease, the examination can be performed at any time as needed. First, to assess the reserve function of insulin secretion by pancreatic B-cells, to detect the control of metabolic indicators, including blood glucose, glycosylated hemoglobin (an important indicator reflecting the overall control of blood glucose in the last 3 months), and blood lipids; second, to assess the development of chronic complications of diabetes, including fundus, kidney damage (detection of urine protein, kidney function), macrovascular lesions (carotid arteries, lower limb arteries, and cardiovascular and cerebrovascular if necessary), neuropathy assessment; third, for the assessment of concomitant morbidity, including blood pressure monitoring, weight/waist circumference, tumor screening (diabetes is a high prevalence of tumors), whether co-infection, etc. In addition, in order to type diabetes, patients who are initially diagnosed are tested for islet autoantibodies. Not all hospitals are equipped to perform these tests and the cost is not small, so they should be performed according to individual circumstances. Finally, it is important to remember that since the tests should be comprehensive, the treatment should also be comprehensive, and some treatments should involve early intervention, rather than tests for the sake of tests.