The most common pathogen that causes female urethritis is E. coli, and the most effective antibiotics for E. coli treatment are quinolones, such as levofloxacin hydrochloride, gatifloxacin, ciprofloxacin, norfloxacin and so on, all of which are commonly used in clinical practice, and also need to be combined with Chinese medicines that have the effect of clearing heat and detoxifying, laxative and diuretic, such as hot gonorrhea Qing granules, Sanjin tablets and so on. The preferred treatment is oral medication, and for more serious infections, intravenous quinolones such as levofloxacin hydrochloride injection and gatifloxacin injection should be used. The urethra of women is shorter, straighter and wider, and they are a common group of people who suffer from urethritis. Women can flush bacteria from the urethra and reduce the symptoms of urethritis by drinking more water and urinating more often, and they can also effectively prevent urethritis.