Taking olanzapine causes elevated aminotransferases may require a change in medication. Olanzapine is a kind of drug for treating mental illness, and liver and kidney function damage may occur after use, especially in the early stage, resulting in transaminase elevation. If the elevation of aminotransferase is mild, it will usually recover after stopping the drug. If the liver function damage is obvious, it is necessary to use liver-protecting drugs such as silymarin capsules, and adjust the dosage of olanzapine if necessary; if the elevation of aminotransferase persists, it is considered that the drug can be changed to a drug that has less effect on liver function. It is recommended that patients seek medical attention as soon as possible after the transaminase is elevated, and the specific change of drug or dosage reduction needs to be carried out under the guidance of the doctor, do not use your own medication, so as not to cause adverse consequences.