After the arrival of the hot summer, many people begin to lose their appetite, see any food feel no appetite, perhaps some people will think that this is a normal reaction of the body after the heat, but people with a history of diabetes, this can not be taken lightly appetite or “gastroparesis” Xiao Lin nearly a month of nausea and vomiting, can not eat, people After a detailed examination, the doctor told her that her diabetes had caused “gastroparesis”. After a month of treatment, Xiaolin’s condition gradually improved and she was able to eat a little. Gastroparesis is a complication of diabetic vegetative neuropathy, said Wei Li, deputy chief physician of the Department of Endocrinology at the Sixth People’s Hospital of Shanghai Jiaotong University School of Medicine, adding that vegetative neuropathy is a common complication of diabetes, seen in more than 50% of diabetic patients. Gastrointestinal motility disorders in patients with diabetic gastroparesis are manifested by the disappearance of mobile motor complex (MMC) phase III of the gastric interdigestive phase and postprandial hypokinesis of the gastric sinus, uncoordinated contractions of the gastric sinus, pylorus and duodenum, and pyloric spasm, which delay the emptying of gastric solids. Early proximal gastric accommodative diastolic dysfunction results in rapid fluid emptying, but in the late phase gastric fluid emptying is also significantly delayed. This may manifest as nausea, vomiting, early satiety, postprandial bloating, abdominal pain, and weight loss. The diagnosis must exclude organic lesions in the upper gastrointestinal tract or upper abdomen. Hyperglycemia, gastrointestinal disease, and improper diet can aggravate the symptoms of gastroparesis The director points out that most patients with early diabetic gastroparesis do not have obvious clinical symptoms, and fewer patients have early satiety, nausea, and postprandial abdominal distension, etc. Symptoms worsen when there are aggravating factors, and vomiting, inability to eat, abdominal pain, and weight loss can occur. Hyperglycemia: Evidence shows that gastric emptying is affected by blood glucose concentration, and increased blood glucose can inhibit the rate of gastric emptying, which inhibits gastric emptying and increases blood glucose level, thus forming a vicious circle; microcirculatory disorders caused by diabetes can also affect the microcirculation of the vegetative nerves, and play a role in promoting the occurrence and development of gastroparesis. Gastrointestinal diseases: Chronic gastritis, reflux esophagitis and other gastrointestinal diseases are also predisposing factors for the aggravation of gastroparesis symptoms. Meanwhile, diabetic patients with gastroparesis are also prone to complications of chronic gastritis and reflux esophagitis. Inappropriate diet: binge eating, over-eating cold and irritating food, eating too hard and greasy food, eating without a fixed time and other bad eating habits can trigger or aggravate the symptoms of gastroparesis. Gastroparesis is a long term process, because once the nerve is damaged, it is difficult to repair, and the treatment is also aimed at improving the symptoms and slowing down the process. Director Wei said that drugs that promote gastric motility and inhibit gastric acid can improve the symptoms of gastroparesis such as bloating, acid reflux and belching, while drugs that improve microcirculation and nerve nutrition can slow down the progress of the disease. In addition, long-term treatment should include the following prevention and control measures: 1. Control of blood glucose Control of blood glucose is the most fundamental measure for the prevention and treatment of gastroparesis. Fasting blood glucose should be reduced to less than 7 mmol/L in elderly patients, 2 hours after meal blood glucose should be reduced to less than 10 mmol/L, and glycosylated hemoglobin should be reduced to less than 7%. The standard of blood sugar control for young patients should be lower, and try to reach the blood sugar level of normal people. 2.Supplementation of B vitamins Gastroparesis is due to the complication of diabetes mellitus with vegetative neuropathy, and B vitamins can be supplemented through drugs or food to nourish the nerves. 3.Eating regular diet Regular and quantitative diet, few and many meals, avoid over-starvation and over-filling, avoid too dry, too hard and coarse fiber-rich food, avoid greasy, raw and cold, stimulating food, choose light and easy to digest food. 4.Regular follow-up Diabetic patients should have regular follow-up hospital checkups to monitor whether blood sugar control is up to standard to avoid complications, and once complications occur, they can be detected early and treated in time to prevent further development.