46-year-old senior pregnant five months before not taking folic acid generally do not need to be overly nervous, you can regularly consult a doctor for examination. 46-year-old senior pregnant women generally need to take folic acid during the preparation for pregnancy and the first three months of pregnancy, taking folic acid can effectively prevent fetal neural tube malformations, if you do not take folic acid do not need to be overly concerned, you can regularly consult a doctor for NT examination, Down’s syndrome examination, four-dimensional ultrasound examination, to understand the development of the fetus. If the development of the fetus is normal and there is no malformation, there is no need to worry too much and terminate the pregnancy. If there are fetal neural tube malformations or other organ malformations, it is recommended to actively seek medical attention to terminate the pregnancy so as not to affect the later growth and development of the infant. During pregnancy, you should follow the doctor’s instructions to take obstetric checkups on time, and if you have any questions, it is recommended that you consult a medical professional for guidance.