Small particles around the nose, if it is acne, you can use topical adapalene gel, azelaic acid ointment and other drugs; folliculitis, you can use topical erythromycin ointment, clotrimazole ointment and other drugs; allergic diseases can be applied glycerine lotion, hydrocortisone ointment and other drugs to treat. 1. Acne: It is related to exuberant secretion of androgen, propagation of Propionibacterium folliculorum, increase of sebaceous glands, and clogging of pores, which may lead to the growth of small particles around the nose. It can be treated with topical medications such as adapalene gel, azelaic acid ointment and retinoic acid ointment. 2. Folliculitis: for example, folliculitis caused by bacterial infection, or folliculitis caused by the reproduction of Malassezia, can also cause small particles around the nose. For bacterial infection, you can use topical erythromycin ointment, mupirocin ointment, and for Malassezia folliculitis, you can use clotrimazole ointment, miconazole cream and other medications. 3. Allergic diseases: such as contact dermatitis, insect bite dermatitis, drug rash, etc., may also lead to small particles around the nose. You can use topical glycerine lotion, hydrocortisone ointment, zinc oxide ointment and other medications. Small particles around the nose may have other causes, it is recommended to go to the hospital in time to check, the drug needs to be used under the guidance of the doctor.