Pediatric eczema is easy to recur, can be cured after standardized treatment, commonly used treatment for drug therapy. Pediatric eczema is due to genetic, environmental, immune and other factors caused by the allergic skin disease, children’s skin is often manifested as erythema, papules, papules, blisters, accompanied by itching. Timely treatment is needed, mainly using medication. Topical medications include glucocorticosteroid drugs such as hydrocortisone, calcium-modulated neural phosphatase inhibitors such as tacrolimus ointment, pimecrolimus cream, etc., which have strong anti-inflammatory effects, and antibiotics such as mupirocin and fusidic acid ointment, etc., which can reduce the infection caused by bacteria or fungi. Pediatric eczema should be treated in time, under the guidance of the doctor with medication, after standardized treatment can be cured, but recurrence is high. Daily attention to the child’s skin dry, clean, eat less spicy and stimulating food. The above drugs need to be used under the guidance of a doctor to avoid unnecessary harm caused by the wrong use.