The black hard skin on the wrist is mostly considered to be scleroderma, patients need to follow the doctor’s instructions for drug treatment, general measures, and if necessary, surgical treatment. 1. Drug treatment: usually patients need to follow the doctor’s instructions to use hydrocortisone, prednisone and other glucocorticoids, and can also be used with methotrexate, cyclophosphamide and other immunosuppressants or prostacyclin, phentolamine, nifedipine and other vasodilators. If the patient has gastrointestinal tract involvement, the patient may also be treated with proton pump inhibitors such as omeprazole and lansoprazole and prokinetic agents such as domperidone and mosapride. If the patient has vomiting, abdominal distension, nausea and malabsorption due to small intestine dysmotility and bacterial overgrowth, antibiotics such as ciprofloxacin, metronidazole and amoxicillin should be used under the guidance of the doctor. 2. General measures: patients need to develop good habits, quit smoking in time, and avoid bad emotions. Patients also need to actively cooperate with the doctor to carry out massage, hot bath and other physical therapy, so as to improve the progressive activity limitation and muscle atrophy. At the same time, the patient also needs to establish a correct knowledge of the disease with the help of the doctor, so as to play an encouraging role. 3. Surgery: If the patient’s condition is more serious, with severe necrosis and finger ulcers, amputation surgery will be required. It is recommended that when patients have the phenomenon of black hard skin on the wrist, they should follow the doctor’s instructions to actively treat the disease and pay more attention to their own care.