Whether a duodenal mass is serious or not can’t be generalized, it needs to be combined with whether the mass is benign or malignant and decided. 1. benign swelling: if it is a benign duodenal swelling, it is not serious, characterized by a slow growth rate of the swelling, its boundaries are clear, the perimeter of the membrane is intact, and generally does not cause the body to have a serious reaction, can be surgically resected to treat, and to achieve curative effects. 2. Malignant swelling: if the duodenum is malignant swelling, its characteristics are the opposite, the swelling is more serious, the growth rate is faster, the border is not clear, the envelope is incomplete, this kind of patients even after surgical resection, there is a possibility of recurrence, and there is the possibility of proliferation and metastasis, there is a danger to life. Therefore, for the discovery of duodenal mass, need to go to the regular hospital in a timely manner, in order to clarify its nature, and then determine whether it is serious, as well as to determine the specific treatment. It is recommended that once detected, active diagnosis and treatment should be carried out to avoid delays.